DNA Binding Motif

Accessions: HOXB2_ELF1_2_3_4_5 (HumanTF2 1.0)
Names: HOXB2_ELF1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: TrAtkrswrsmGGAAGtr
Weblogo:
PSSM: P0 A C G T
01 139 69 75 759 T
02 759 70 361 180 r
03 759 7 25 1 A
04 69 157 144 759 t
05 97 169 465 294 k
06 312 146 447 163 r
07 168 232 204 156 s
08 266 107 172 214 w
09 209 179 195 177 r
10 183 221 255 100 s
11 236 393 109 21 m
12 4 6 759 0 G
13 0 0 759 19 G
14 759 7 0 45 A
15 759 21 1 95 A
16 161 107 759 15 G
17 205 360 230 759 t
18 201 133 297 129 r
Type: Heterodimer
Binding TFs: ELF1_TF2 (Ets-domain, Transcription factor protein N terminal)
HOXB2_TF1 (Homeobox domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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