DNA Binding Motif

						

			
Accessions: 6hb4_J (3D-footprint 20231221)

			
Names: Transcription factor A, mitochondrial
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: TFAM in Complex with Site-Y
Length: 18
Consensus: AATTGAnnnnnnnnACAG
Weblogo: 
PSSM: P0      A      C      G      T
01     73      9      7      7      A
02     96      0      0      0      A
03      7      7      7     75      T
04      0      0      0     96      T
05      0      0     96      0      G
06     75      7      7      7      A
07     24     24     24     24      n
08     24     24     24     24      n
09     24     24     24     24      n
10     24     24     24     24      n
11     24     24     24     24      n
12     24     24     24     24      n
13     24     24     24     24      n
14     24     24     24     24      n
15     96      0      0      0      A
16      0     96      0      0      C
17     96      0      0      0      A
18      9      7     73      7      G
Binding TFs: 6hb4_J (HMG (high mobility group) box, Domain of unknown function (DUF1898))
			
Publications: Cuppari A, Fernández-Millán P, Battistini F, Tarrés-Solé A, Lyonnais S, Iruela G, Ruiz-López E, Enciso Y, Rubio-Cosials A, Prohens R, Pons M, Alfonso C, Tóth K, Rivas G, Orozco M, Solà M. DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control region. Nucleic Acids Res 47:6519-6537 (2019). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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