DNA Binding Motif

						

			
Accessions: 3cbb_A (3D-footprint 20231221)

			
Names: Hepatocyte Nuclear Factor 4-alpha, DNA binding domain
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of Hepatocyte Nuclear Factor 4alpha in complex with DNA: Diabetes Gene Product
Length: 5
Consensus: GTCCA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02      9     11      9     67      T
03      9     69      9      9      C
04      0     96      0      0      C
05     67     11      9      9      A
Binding TFs: 3cbb_A (Zinc finger, C4 type (two domains))
Binding Sites: 3cbb_C
3cbb_D
			
Publications: Lu P, Rha G.B, Melikishvili M, Wu G, Adkins B.C, Fried M.G, Chi Y.I. Structural basis of natural promoter recognition by a unique nuclear receptor, HNF4alpha. Diabetes gene product. The Journal of biological chemistry 283:33685-97 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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