DNA Binding Motif

						

			
Accessions: 6jni_GH (3D-footprint 20231221)

			
Names: CadR
Organisms: Pseudomonas putida
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the transcriptional regulator CadR from P. putida in complex with Zinc(II) and DNA
Length: 21
Consensus: ACnnTATAGTnGCTACAnnGT
Weblogo: 
PSSM: P0      A      C      G      T
01     72     10      4     10      A
02      2     89      2      3      C
03     24     24     24     24      n
04     24     24     24     24      n
05      2      2      2     90      T
06     74      8     10      4      A
07      0      0      0     96      T
08     96      0      0      0      A
09      0      0     96      0      G
10      2      2      2     90      T
11     24     24     24     24      n
12      2      2     89      3      G
13      0     96      0      0      C
14      2      3      2     89      T
15     96      0      0      0      A
16      2     89      3      2      C
17     91      2      0      3      A
18     24     24     24     24      n
19     24     24     24     24      n
20      3      2     89      2      G
21     10      4      2     80      T
Type: Heterodimer
Binding TFs: 6jni_G (MerR family regulatory protein, MerR, DNA binding, MerR HTH family regulatory protein)
6jni_H (MerR family regulatory protein, MerR, DNA binding, MerR HTH family regulatory protein)
Binding Sites: 6jni_O
6jni_P
			
Publications: Liu X, Hu Q, Yang J, Huang S, Wei T, Chen W, He Y, Wang D, Liu Z, Wang K, Gan J, Chen H. Selective cadmium regulation mediated by a cooperative binding mechanism in CadR. Proc Natl Acad Sci U S A 116:20398-20403 (2019). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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