DNA Binding Motif

Accessions: 5x5l_AE (3D-footprint 20231221)
Names: AdeR
Organisms: Acinetobacter baumannii
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of response regulator AdeR DNA binding domain in complex with an intercistronic region
Length: 20
Consensus: AAnnTGTGGnnnAAGTGnGG
Weblogo:
PSSM: P0 A C G T
01 79 2 5 10 A
02 96 0 0 0 A
03 24 24 24 24 n
04 24 24 24 24 n
05 2 2 5 87 T
06 2 13 76 5 G
07 0 0 0 96 T
08 0 0 96 0 G
09 2 2 90 2 G
10 24 24 24 24 n
11 24 24 24 24 n
12 24 24 24 24 n
13 96 0 0 0 A
14 68 10 8 10 A
15 0 0 96 0 G
16 2 2 2 90 T
17 8 10 71 7 G
18 24 24 24 24 n
19 0 0 96 0 G
20 0 0 94 2 G
Type: Heterodimer
Binding TFs: 5x5l_A (Transcriptional regulatory protein, C terminal)
5x5l_E (Transcriptional regulatory protein, C terminal)
Binding Sites: 5x5l_F
5x5l_G
Publications: Wen Y, Ouyang Z, Yu Y, Zhou X, Pei Y, Devreese B, Higgins PG, Zheng F. Mechanistic insight into how multidrug resistant Acinetobacter baumannii response regulator AdeR recognizes an intercistronic region. Nucleic Acids Res 45:9773-9787 (2017). [Pubmed]

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