DNA Binding Motif

						

			
Accessions: 3rkq_B (3D-footprint 20231221)

			
Names: Homeobox protein Nkx-2.5
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: NKX2.5 Homeodomain dimer bound to ANF-242 DNA
Length: 7
Consensus: CTCTtGA
Weblogo: 
PSSM: P0      A      C      G      T
01      6     78      6      6      C
02      6      0      0     90      T
03      0     96      0      0      C
04      0      0      0     96      T
05      6     12     18     60      t
06     18      6     72      0      G
07     72      6     12      6      A
Binding TFs: 3rkq_B (Homeobox domain)
Binding Sites: 3rkq_C
3rkq_D
			
Publications: Pradhan L, Genis C, Scone P, Weinberg E.O, Kasahara H, Nam H.J. Crystal structure of the human NKX2.5 homeodomain in complex with DNA target. Biochemistry 51:6312-9 (2012). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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