DNA Binding Motif

Accessions: 3rkq_B (3D-footprint 20231221)
Names: Homeobox protein Nkx-2.5
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: NKX2.5 Homeodomain dimer bound to ANF-242 DNA
Length: 7
Consensus: CTCTtGA
01 6 78 6 6 C
02 6 0 0 90 T
03 0 96 0 0 C
04 0 0 0 96 T
05 6 12 18 60 t
06 18 6 72 0 G
07 72 6 12 6 A
Binding TFs: 3rkq_B (Homeobox domain)
Binding Sites: 3rkq_C
Publications: Pradhan L, Genis C, Scone P, Weinberg E.O, Kasahara H, Nam H.J. Crystal structure of the human NKX2.5 homeodomain in complex with DNA target. Biochemistry 51:6312-9 (2012). [Pubmed]

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