DNA Binding Motif
| Accessions: | MA0597.2 (JASPAR 2024) |
| Names: | THAP1 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 12 |
| Consensus: | ssgcAGGGCAss |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 960 1549 1884 785 s 02 838 1854 1667 819 s 03 477 966 3186 549 g 04 553 3351 933 341 c 05 4731 219 220 8 A 06 22 127 4958 71 G 07 40 183 4893 62 G 08 91 67 4942 78 G 09 98 4861 104 115 C 10 4900 95 172 11 A 11 675 1472 2374 657 s 12 979 1606 1870 723 s |
| Type: | Heterodimer |
| Binding TFs: | Q9NVV9 (THAP domain) Q9NVV9 |
| Binding Sites: | MA0597.2.1 MA0597.2.10 MA0597.2.11 MA0597.2.12 MA0597.2.13 MA0597.2.14 MA0597.2.15 MA0597.2.16 MA0597.2.17 MA0597.2.18 MA0597.2.19 MA0597.2.2 MA0597.2.20 MA0597.2.3 MA0597.2.4 MA0597.2.5 MA0597.2.6 MA0597.2.7 MA0597.2.8 MA0597.2.9 |
| Publications: | Clouaire T, Roussigne M, Ecochard V, Mathe C, Amalric F, Girard J.P. The THAP domain of THAP1 is a large C2CH module with zinc-dependent sequence-specific DNA-binding activity. Proceedings of the National Academy of Sciences of the United States of America 102:6907-12 (2005). [Pubmed] |
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