DNA Binding Motif

						

			
Accessions: KLF17_3 (HT-SELEX2 May2017), MA1514.1 (JASPAR 2024)

			
Names: KLF17
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1, JASPAR 2024 2
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 15
Consensus: mmCCACgCaCCCmty
Weblogo: 
PSSM: P0      A      C      G      T
01   8969  14366   3318   3579      m
02  19057   9728   2102   2132      m
03    221  30181    122    114      C
04    144  30201    105     87      C
05  28922    197     84   2495      A
06     85  30107     53    423      C
07   7236   6958  24407   1243      g
08   4563  29153    104    373      C
09  19142   1076   5176   8373      a
10    827  29551   1410    220      C
11    132  30200    201     57      C
12    221  30199     80    233      C
13  12266  14825   3845   3318      m
14   3892   4873   2368  23588      t
15   4465   9629   2851  17959      y
Type: Heterodimer
Binding TFs: KLF17 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Q5JT82 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Q5JT82
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]


Bieker JJ. Krüppel-like factors: three fingers in many pies. J Biol Chem 276:34355-8 (2001). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.