DNA Binding Motif

Accessions: ELK1_TBX21_1 (HumanTF2 1.0)
Names: ELK1_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 31
Consensus: aaGGtGtgrmrkkkmkttmrCrcCGGAAGyg
Weblogo:
PSSM: P0 A C G T
01 1668 380 883 832 a
02 2840 391 780 195 a
03 311 336 2799 403 G
04 192 170 2859 207 G
05 330 907 374 2787 t
06 140 94 2780 159 G
07 774 1147 899 3062 t
08 264 688 1664 274 g
09 1721 115 818 236 r
10 1023 898 319 650 m
11 758 635 944 554 r
12 582 610 769 930 k
13 709 469 986 727 k
14 453 325 1191 923 k
15 757 1006 560 567 m
16 459 690 932 811 k
17 615 633 664 979 t
18 275 525 199 1892 t
19 1325 871 607 88 m
20 1359 247 841 444 r
21 99 2657 79 55 C
22 1941 44 899 6 r
23 483 1739 626 43 c
24 295 2792 21 15 C
25 0 11 2893 0 G
26 0 3 2887 21 G
27 2885 13 0 21 A
28 2769 31 42 347 A
29 508 298 2650 18 G
30 427 1093 586 1772 y
31 462 333 1613 483 g
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
TBX21_TF2 (T-box)
ELK1_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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