DNA Binding Motif

						

			
Accessions: ERF_TBX21_2 (HumanTF2 1.0), UN0508.1 (JASPAR 2024)

			
Names: ERF_TBX21, ERF::TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 12
Consensus: TmaCACCGGAAr
Weblogo: 
PSSM: P0      A      C      G      T
01   1590   2281   1775  14423      T
02   6632   7995   2526   1011      m
03  12957   1846   4128   1506      a
04   1667  14383   1442    892      C
05  14399    685   3675    501      A
06    603  14764   1102    269      C
07   3616  13391    315      0      C
08     54      0  14907    134      G
09      0     11  14900    415      G
10  14882     46     73      0      A
11  14345    549     58   3777      A
12   5705   2937  10248    281      r
Type: Heterodimer
Binding TFs: TBX21_TF2 (T-box)
ERF_TF1 (Ets-domain)
Q9UL17 (T-box)
Q9UL17
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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