DNA Binding Motif

						

			
Accessions: GCM1_FIGLA_2_3_4_5_6_7_8 (HumanTF2 1.0)

			
Names: GCM1_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: CASsTGykmkkrkvrTGCGGG
Weblogo: 
PSSM: P0      A      C      G      T
01     15   1610      0      0      C
02   1610      5      0     18      A
03      0    633   1610     25      S
04     24   1610   1409      6      s
05      1      2     25   1610      T
06      0      3   1610      9      G
07    114    490    287    720      y
08    126    220    525    740      k
09    529    563    364    154      m
10    176    397    604    433      k
11    272    256    427    655      k
12    835    196    425    154      r
13    322    155    611    522      k
14    477    474    547    113      v
15    962     73    564     11      r
16     44     56     42   1610      T
17    316     35   1610      8      G
18    179   1610    163    128      C
19    118     38   1610    183      G
20     10     12   1610      5      G
21      0     10   1610     20      G
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
GCM1_TF1 (GCM motif protein)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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