DNA Binding Motif

Accessions: UP00058A_2 (UniPROBE 20160601)
Names: HMG box transcription factor 3, mTCF-3, Tcf3, Tcf7l1, transcription factor 3, Transcription factor 7-like 1
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 15
Consensus: rgssgaawawaaaww
Weblogo:
PSSM: P0 A C G T
01 0.34 0.18 0.28 0.20 r
02 0.19 0.24 0.39 0.18 g
03 0.13 0.37 0.36 0.14 s
04 0.11 0.48 0.35 0.06 s
05 0.19 0.21 0.39 0.21 g
06 0.50 0.11 0.19 0.20 a
07 0.53 0.13 0.21 0.13 a
08 0.43 0.18 0.10 0.28 w
09 0.54 0.14 0.11 0.21 a
10 0.40 0.18 0.12 0.31 w
11 0.53 0.20 0.15 0.12 a
12 0.49 0.17 0.15 0.20 a
13 0.53 0.17 0.18 0.12 a
14 0.35 0.17 0.14 0.34 w
15 0.26 0.22 0.19 0.33 w
Binding TFs: UP00058A (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Binding Sites: AACATCAA
AAGATCAA
AATCAAAG
ACATCAAA
ACTTCAAA
ACTTTGAT
AGATCAAA
AGATCAAT
ATCAAAGA
ATCAAAGC
ATCAAAGG
CATCAAAG
CCTTTGAA
CTTCAAAG
CTTTGATA
CTTTGATC
GAGATCAA
GATCAAAA
GGATCAAA
TGATCAAA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

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