DNA Binding Motif

						

			
Accessions: ETV2_EOMES_1 (HumanTF2 1.0)

			
Names: ETV2_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 30
Consensus: agGYGtkamvtksmrttsrCrcMGGAwryg
Weblogo: 
PSSM: P0      A      C      G      T
01    885    384    527    373      a
02    890    807   2169    590      g
03    134    239   2169    299      G
04     45    855     55   2169      Y
05     41      9   2169      9      G
06    638    998    678   2169      t
07    196    423    875    674      k
08   1160    184    493    332      a
09    723    619    468    360      m
10    549    577    610    433      v
11    465    439    407    858      t
12    387    513    647    622      k
13    530    572    781    286      s
14    588    598    483    501      m
15    616    442    723    389      r
16    457    487    498    728      t
17    245    434    189   1300      t
18    362    908    672    227      s
19    837    199    694    439      r
20     59   2018     30     62      C
21   1389     29    727     24      r
22    538   2169    420     84      c
23    762   2169     61      0      M
24      4     11   2169      3      G
25      5      3   2169     25      G
26   2169      1      0     24      A
27   1255    134     18    914      w
28    763    144   1170     92      r
29    257    719    256    936      y
30    348    482    924    415      g
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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