DNA Binding Motif
| Accessions: | 5mez_A (3D-footprint 20231221) |
| Names: | MH1 domain of human Smad4 |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Description: | Crystal structure of Smad4-MH1 bound to the GGCT site. |
| Length: | 5 |
| Consensus: | GgCTa |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0 0 84 12 G 02 12 12 60 12 g 03 0 96 0 0 C 04 0 0 0 96 T 05 60 12 12 12 a |
| Binding TFs: | 5mez_A (MH1 domain) |
| Binding Sites: | 5mez_D / 5mez_E |
| Publications: | Martin-Malpartida P, Batet M, Kaczmarska Z, Freier R, Gomes T, Aragón E, Zou Y, Wang Q, Xi Q, Ruiz L, Vea A, Márquez JA, Massagué J, Macias MJ. Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun 8:2070 (2017). [Pubmed] |
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