DNA Binding Motif

						

			
Accessions: ELK1_HOXA1_2 (HumanTF2 1.0)

			
Names: ELK1_HOXA1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: HT-SELEX; PWM is from validation experiment performed with full-length TFs and is not included into the dendrograms
Length: 14
Consensus: rCCGGAAGTvaTya
Weblogo: 
PSSM: P0      A      C      G      T
01    262     23    156     21      r
02     36    418     98     17      C
03      0    418      0      2      C
04      1      2    418      0      G
05      0      2    418      9      G
06    418      1      0      5      A
07    418      6      0     88      A
08      0     18    418      2      G
09      0     63      0    418      T
10    418    288    289     92      v
11    418     88    111     47      a
12     18     34     89    418      T
13     55    285     75    418      y
14    418     73    126     69      a
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
HOXA1_TF2 (Homeobox domain)
ELK1_TF1 (Ets-domain)
HOXA1_Full (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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