DNA Binding Motif

						

			
Accessions: CUX1_TBX21_1 (HumanTF2 1.0)

			
Names: CUX1_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: kTcACACmyyrATCrATm
Weblogo: 
PSSM: P0      A      C      G      T
01    144    126    378    321      k
02     83    190     21    968      T
03    286    968    293     65      c
04    968     35     52     44      A
05      0    968     13     20      C
06    968     14     99     11      A
07     38    968     20      8      C
08    499    469    151    324      m
09    134    285     35    514      y
10     18    292    119    539      y
11    490     26    298    154      r
12    968      5      0      0      A
13      0      9    178    968      T
14      2    968      0      7      C
15    364      4    604      5      r
16    968      0      0     16      A
17    108      0      3    968      T
18    420    330    157     61      m
Type: Heterodimer
Binding TFs: CUX1_TF1 (Homeobox domain, CUT domain, Homeobox KN domain)
TBX21_TF2 (T-box)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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