DNA Binding Motif

						

			
Accessions: ETV2_GSC2_2_3 (HumanTF2 1.0)

			
Names: ETV2_GSC2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: rcCGGAAryscmmcTAATcym
Weblogo: 
PSSM: P0      A      C      G      T
01    412    101    279    151      r
02    213    691    212     49      c
03    148    691      1      0      C
04      3      0    691      0      G
05      9      6    691      0      G
06    691      7      0     13      A
07    495     68      0    127      A
08    350      7    335      0      r
09     59    271     69    292      y
10    103    184    272    132      s
11    149    322    154     66      c
12    182    302    132     75      m
13    200    274     65    151      m
14     86    436     52    117      c
15     92     32      0    691      T
16    691      9     27     34      A
17    691      0      5      0      A
18     65     33    211    691      T
19    191    691    150     85      c
20    177    691    162    356      y
21    254    177    122    138      m
Type: Heterodimer
Binding TFs: GSC2_TF2 (Homeobox domain)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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