DNA Binding Motif

Accessions: 1jj4_B (3D-footprint 20231221)
Names: Regulatory protein E2
Organisms: Human papillomavirus type 18
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Human papillomavirus type 18 E2 DNA-binding domain bound to its DNA target
Length: 6
Consensus: CGGTtG
Weblogo:
PSSM: P0 A C G T
01 10 69 0 17 C
02 0 0 96 0 G
03 0 0 87 9 G
04 0 0 0 96 T
05 19 8 8 61 t
06 11 8 69 8 G
Binding TFs: 1jj4_B (E2 (early) protein, C terminal)
Binding Sites: 1jj4_C / 1jj4_D
Publications: Kim S.S, Tam J.K, Wang A.F, Hegde R.S. The structural basis of DNA target discrimination by papillomavirus E2 proteins. The Journal of biological chemistry 275:31245-54 (2000). [Pubmed]

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