DNA Binding Motif

Accessions: UP00098A_1 (UniPROBE 20160601)
Names: 3 (influences HLA class II expression), C230093O12Rik, MRFX3, regulatory factor X, Rfx3, Transcription factor RFX3
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 23
Consensus: tdtsmycChTAGCAACsrwwhww
Weblogo:
PSSM: P0 A C G T
01 0.22 0.23 0.15 0.40 t
02 0.26 0.13 0.32 0.29 d
03 0.12 0.19 0.17 0.52 t
04 0.11 0.28 0.41 0.20 s
05 0.34 0.31 0.12 0.22 m
06 0.19 0.37 0.16 0.28 y
07 0.17 0.58 0.13 0.12 c
08 0.01 0.93 0.05 0.02 C
09 0.26 0.29 0.13 0.33 h
10 0 0.01 0 0.98 T
11 0.85 0.01 0.14 0 A
12 0.04 0 0.96 0 G
13 0.01 0.92 0 0.07 C
14 0.94 0 0.04 0.01 A
15 0.99 0 0 0 A
16 0 0.99 0 0.01 C
17 0.21 0.37 0.32 0.10 s
18 0.32 0.19 0.37 0.12 r
19 0.33 0.18 0.23 0.27 w
20 0.30 0.19 0.13 0.38 w
21 0.30 0.27 0.10 0.34 h
22 0.42 0.19 0.13 0.26 w
23 0.39 0.20 0.13 0.28 w
Binding TFs: UP00098A (RFX DNA-binding domain)
Binding Sites: ATAGCAAC
ATGGCAAC
ATGGTTAC
CGTAACTA
CGTTACCA
CGTTACTA
CGTTGCCA
CGTTGCTA
CTAGCAAC
GGTAACCA
GGTAACTA
GGTTACCA
GGTTGCCA
GGTTGCTA
GTAGCAAC
GTTACCAA
GTTACTAA
GTTGCCAA
GTTGCTAA
TAGCAACA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

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