DNA Binding Motif

						

			
Accessions: POU2F1_TBX21_1 (HumanTF2 1.0)

			
Names: POU2F1_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: hgTGydrgmATATkmthaCAcc
Weblogo: 
PSSM: P0      A      C      G      T
01   1993   1343    470   1311      h
02    196   1367   4480   1668      g
03     85   1494    237   4814      T
04     92     37   5091    252      G
05    741   1705    933   1737      y
06   1451    808   1312   1546      d
07   2578    251   1674    615      r
08   1214    634   2144   1125      g
09   3541   1575     21    353      m
10   5018     42     52    382      A
11     11      2    118   5116      T
12   5116     11     96     71      A
13     42     80      0   5041      T
14     96     82   1542   3575      k
15   1472   2306    477    862      m
16    999   1057    514   2547      t
17   1902   1293     92   1830      h
18   4425    108    611   1413      a
19     28   5104      9     44      C
20   4822     30   1420    109      A
21   1389   4299    941     67      c
22   1262   4048   1801   1679      c
Type: Heterodimer
Binding TFs: POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
TBX21_TF2 (T-box)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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