DNA Binding Motif

						

			
Accessions: MA0686.2 (JASPAR 2024)

			
Names: SPDEF
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 10
Consensus: AmCCGGATgT
Weblogo: 
PSSM: P0      A      C      G      T
01   4628    101    176    912      A
02   1890   2737    536     77      m
03     52   4628     92      0      C
04    237   4628      1      1      C
05      2      2   4628      0      G
06      6      0   4628      8      G
07   4628      0      6      2      A
08    532     69     11   4628      T
09   1566    601   4628     66      g
10     58   1345     28   4628      T
Type: Heterodimer
Binding TFs: O95238 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
O95238
			
Publications: Pal M, Koul S, Koul HK. The transcription factor sterile alpha motif (SAM) pointed domain-containing ETS transcription factor (SPDEF) is required for E-cadherin expression in prostate cancer cells. J Biol Chem 288:12222-31 (2013). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.