DNA Binding Motif
| Accessions: | UP00014A_1 (UniPROBE 20160601), UP00069A_11 (UniPROBE 20160601) |
| Names: | Sox-17, Sox17, SRY-box containing gene 17, Transcription factor SOX-17, Sox-1, SOX-1 protein, Sox1, SRY-box containing gene 1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Length: | 15 |
| Consensus: | mwaAACAATTrAwhw |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0.38 0.28 0.18 0.15 m 02 0.31 0.15 0.18 0.36 w 03 0.48 0.06 0.24 0.22 a 04 0.77 0.08 0.08 0.08 A 05 0.72 0.02 0.02 0.24 A 06 0.02 0.86 0.04 0.09 C 07 0.95 0.01 0.01 0.03 A 08 0.97 0 0.01 0.02 A 09 0.02 0.01 0.01 0.96 T 10 0.18 0.02 0.08 0.72 T 11 0.39 0.17 0.35 0.09 r 12 0.69 0.09 0.08 0.15 A 13 0.42 0.10 0.06 0.42 w 14 0.27 0.31 0.12 0.30 h 15 0.39 0.12 0.18 0.31 w |
| Type: | Heterodimer |
| Binding TFs: | UP00014A (HMG (high mobility group) box, Domain of unknown function (DUF1898)) UP00069A (HMG (high mobility group) box, Domain of unknown function (DUF1898), SOX transcription factor) |
| Binding Sites: | AAAACAAT AAACAAAG AAACAATT AACAAAGA AACAATAA AACAATAG AACAATAT AACAATGG AACAATTA AACAATTC AACAATTG AAGACAAT AATTCAAT AATTGTTA AATTGTTC ACAAAGAA ACAAAGGA ACAACAAT ACAATTGA ACAATTGT AGAACAAT AGACAATA ATAACAAT ATGAATTG ATTGTTAA ATTGTTCA CATTGTTC CTTTGTTC GAACAATA GACAAAGA TAACAATA ATTGTCTC |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
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