DNA Binding Motif

						

			
Accessions: GCM1_ELF1_2_3 (HumanTF2 1.0), UN0540.1 (JASPAR 2024)

			
Names: GCM1_ELF1, GCM1::ELF1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 16
Consensus: crCCCrCACGGAAGtr
Weblogo: 
PSSM: P0      A      C      G      T
01     83    201     82    114      c
02    272     46    208     28      r
03      0    480     44      0      C
04     37    480     47      0      C
05     38    480     78     51      C
06    140      0    340     61      r
07      6    378     11     85      C
08    359     29     94      0      A
09      9    480     12      0      C
10      0     29    480      0      G
11     14      0    480     22      G
12    480     31      0      0      A
13    480      0      0     47      A
14     81     72    480      0      G
15     20     70     65    325      t
16    131     76    196     78      r
Type: Heterodimer
Binding TFs: ELF1_TF2 (Ets-domain, Transcription factor protein N terminal)
GCM1_TF1 (GCM motif protein)
Q9NP62 (GCM motif protein)
Q9NP62
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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