DNA Binding Motif

						

			
Accessions: MA1990.2 (JASPAR 2024)

			
Names: Gli1
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 10
Consensus: rGACCACCCA
Weblogo: 
PSSM: P0      A      C      G      T
01   2124    299   1104    476      r
02    113    193   3535    162      G
03   3120    331    498     54      A
04    100   3744     88     71      C
05     71   3809     74     49      C
06   3653     73     87    190      A
07     38   3827     75     63      C
08    559   3231    145     68      C
09    153   3566    110    174      C
10   3312    188    251    252      A
Type: Heterodimer
Binding TFs: P47806 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
P47806
Binding Sites: MA1990.2.1 / MA1990.2.2
MA1990.2.10
MA1990.2.11 / MA1990.2.16 / MA1990.2.4
MA1990.2.12
MA1990.2.13
MA1990.2.14 / MA1990.2.19 / MA1990.2.3 / MA1990.2.9
MA1990.2.15 / MA1990.2.8
MA1990.2.17
MA1990.2.18
MA1990.2.20
MA1990.2.5
MA1990.2.6
MA1990.2.7
			
Publications: Infante P, Mori M, Alfonsi R, Ghirga F, Aiello F, Toscano S, Ingallina C, Siler M, Cucchi D, Po A, Miele E, D'Amico D, Canettieri G, De Smaele E, Ferretti E, Screpanti I, Uccello Barretta G, Botta M, Botta B, Gulino A, Di Marcotullio L. Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors. EMBO J 34:200-17 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.