DNA Binding Motif

						

			
Accessions: CUX1_RFX5_2 (HumanTF2 1.0)

			
Names: CUX1_RFX5
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: rATCRATracktsCcTAGyAAC
Weblogo: 
PSSM: P0      A      C      G      T
01   1163    105    943    103      r
02   2106      0     16     49      A
03      1      2      1   2106      T
04      1   2106      0     30      C
05    589      3   1518     24      R
06   2106      1      6     11      A
07     51      3      2   2106      T
08    922    177    796    211      r
09   1126    458    224    298      a
10    310    932    400    465      c
11    285    365    835    622      k
12    410    413    349    933      t
13    424    536    945    202      s
14     59   1648    204    195      C
15    493    974    456    184      c
16    158     97     27   1824      T
17   1611     80    495     92      A
18    163     82   2106    106      G
19     55    833     27   1273      y
20   2106     61    106     77      A
21   2106     59     40    107      A
22     38   2106     42    160      C
Type: Heterodimer
Binding TFs: CUX1_TF1 (Homeobox domain, CUT domain, Homeobox KN domain)
RFX5_TF2 (RFX DNA-binding domain, Poxvirus D5 protein-like)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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