DNA Binding Motif

						

			
Accessions: GCM1_MAX_2_3_4_5_6 (HumanTF2 1.0)

			
Names: GCM1_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: aTGCGGGyrggrrgCACGTGs
Weblogo: 
PSSM: P0      A      C      G      T
01   3140    552   1022    219      a
02    146    244    166   4161      T
03   1171    150   4161      5      G
04    705   4161    568    464      C
05    236    154   4161   1123      G
06     17     45   4161     45      G
07     18      9   4161     41      G
08    189   1668    124   2180      y
09   1596    587   1364    614      r
10    638    726   1914    883      g
11    857    795   1565    944      g
12   1209    519   1468    966      r
13   1194    839   1348    781      r
14    624    584   2143    809      g
15     35   4161      0      7      C
16   4161     57     99     30      A
17      0   4161      3    243      C
18    116     14   4161      4      G
19     17     61     22   4161      T
20     11      0   4161     65      G
21    374   1106   1732    950      s
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
MAX_TF2 (Helix-loop-helix DNA-binding domain)
MAX_Full (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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