DNA Binding Motif
| Accessions: | Spo0A (DBTBS 1.0) |
| Names: | Spo0A |
| Organisms: | Bacillus subtilis |
| Libraries: | DBTBS 1.0 1 1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed] |
| Length: | 7 |
| Consensus: | TGtCGAA |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0.08 0.16 0 0.76 T 02 0.06 0 0.94 0 G 03 0.18 0.15 0 0.67 t 04 0 0.89 0 0.11 C 05 0.02 0 0.98 0 G 06 0.91 0 0 0.09 A 07 0.73 0 0.24 0.03 A |
| Binding TFs: | Spo0A (His Kinase A (phospho-acceptor) domain, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase) |
| Binding Sites: | abrB_4 dltA_3 kinA_2 kinC_2 sinI_6 spo0A_4 spo0A_5 spo0A_6 spo0F_3 spo0F_4 spoIIAA_2 spoIIAA_3 spoIIAA_4 spoIIAA_5 spoIIE_2 spoIIE_3 spoIIE_4 spoIIE_5 spoIIGA_2 spoIIGA_3 spoIIGA_4 spoIIGA_5 ybcO_2 yuxH_2 |
| Publications: | Strauch M, Webb V, Spiegelman G, Hoch J.A. The SpoOA protein of Bacillus subtilis is a repressor of the abrB gene. Proceedings of the National Academy of Sciences of the United States of America 87:1801-5 (1990). [Pubmed] Fujita M, González-Pastor J.E, Losick R. High- and low-threshold genes in the Spo0A regulon of Bacillus subtilis. Journal of bacteriology 187:1357-68 (2005). [Pubmed] Perego M, Glaser P, Minutello A, Strauch M.A, Leopold K, Fischer W. Incorporation of D-alanine into lipoteichoic acid and wall teichoic acid in Bacillus subtilis. Identification of genes and regulation. The Journal of biological chemistry 270:15598-606 (1995). [Pubmed] Fujita M, Sadaie Y. Feedback loops involving Spo0A and AbrB in in vitro transcription of the genes involved in the initiation of sporulation in Bacillus subtilis. Journal of biochemistry 124:98-104 (1998). [Pubmed] Kobayashi K, Shoji K, Shimizu T, Nakano K, Sato T, Kobayashi Y. Analysis of a suppressor mutation ssb (kinC) of sur0B20 (spo0A) mutation in Bacillus subtilis reveals that kinC encodes a histidine protein kinase. Journal of bacteriology 177:176-82 (1995). [Pubmed] Shafikhani S.H, Mandic-Mulec I, Strauch M.A, Smith I, Leighton T. Postexponential regulation of sin operon expression in Bacillus subtilis. Journal of bacteriology 184:564-71 (2002). [Pubmed] Strauch M.A, Trach K.A, Day J, Hoch J.A. Spo0A activates and represses its own synthesis by binding at its dual promoters. Biochimie 74:619-26 (). [Pubmed] Strauch M.A, Wu J.J, Jonas R.H, Hoch J.A. A positive feedback loop controls transcription of the spoOF gene, a component of the sporulation phosphorelay in Bacillus subtilis. Molecular microbiology 7:967-74 (1993). [Pubmed] Baldus J.M, Green B.D, Youngman P, Moran C.P. Phosphorylation of Bacillus subtilis transcription factor Spo0A stimulates transcription from the spoIIG promoter by enhancing binding to weak 0A boxes. Journal of bacteriology 176:296-306 (1994). [Pubmed] York K, Kenney T.J, Satola S, Moran C.P, Poth H, Youngman P. Spo0A controls the sigma A-dependent activation of Bacillus subtilis sporulation-specific transcription unit spoIIE. Journal of bacteriology 174:2648-58 (1992). [Pubmed] Chen G, Kumar A, Wyman T.H, Moran C.P. Spo0A-dependent activation of an extended -10 region promoter in Bacillus subtilis. Journal of bacteriology 188:1411-8 (2006). [Pubmed] Molle V, Fujita M, Jensen S.T, Eichenberger P, González-Pastor J.E, Liu J.S, Losick R. The Spo0A regulon of Bacillus subtilis. Molecular microbiology 50:1683-701 (2003). [Pubmed] |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.