DNA Binding Motif

						

			
Accessions: HOXB2_ESRRB_2 (HumanTF2 1.0)

			
Names: HOXB2_ESRRB
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: TAATkrcswbyCAAGGTCA
Weblogo: 
PSSM: P0      A      C      G      T
01     44     37     10    405      T
02    405     58     37      4      A
03    405      0      4      0      A
04      4      9     13    405      T
05      0     27    200    205      k
06    242     26    162     35      r
07     85    149     96     74      c
08     39    133    148     84      s
09    117     67     99    122      w
10     54    104    104    143      b
11     45    124     28    208      y
12      0    336     68      1      C
13    405      5     44     16      A
14    405     11     12      6      A
15      9      2    405      8      G
16      4      0    405      0      G
17      0      3     43    405      T
18     12    405     22     26      C
19    405      0     64      1      A
Type: Heterodimer
Binding TFs: ESRRB_TF1 / ESRRB_TF2 (Zinc finger, C4 type (two domains))
HOXB2_TF1 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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