DNA Binding Motif

Accessions: UP00035A_1 (UniPROBE 20160601)
Names: AA408311, Hic-1, Hic1, hypermethylated in cancer 1, Hypermethylated in cancer 1 protein
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: dykrTGCCAaCCtrcy
Weblogo:
PSSM: P0 A C G T
01 0.28 0.21 0.25 0.26 d
02 0.14 0.33 0.22 0.32 y
03 0.15 0.24 0.27 0.34 k
04 0.66 0.01 0.32 0.02 r
05 0 0 0 0.99 T
06 0.04 0 0.96 0 G
07 0 0.97 0.02 0 C
08 0 0.99 0 0 C
09 0.92 0.07 0 0.01 A
10 0.58 0.21 0.12 0.09 a
11 0.01 0.93 0.03 0.04 C
12 0.03 0.80 0.05 0.12 C
13 0.20 0.19 0.17 0.44 t
14 0.40 0.15 0.29 0.15 r
15 0.20 0.41 0.15 0.24 c
16 0.24 0.33 0.14 0.28 y
Binding TFs: UP00035A (Zinc finger, C2H2 type, C2H2 type zinc-finger (2 copies), Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Binding Sites: AGGTGGCA
AGTTGGCA
ATGCCAAC
ATGCCACC
ATGCCAGC
ATGCCCAC
ATGCCCAT
ATTGGCAC
CGTTGGCA
GATGCCCA
GGGTGGCA
GGTGCCCA
GGTGGCAC
GGTGGGCA
GGTTGGCA
GTGCCCAC
TGCCCACA
TGGGCACA
TGTGCCAA
GGTGCCAA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

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