DNA Binding Motif

Accessions: MYBL1_FIGLA_2 (HumanTF2 1.0)
Names: MYBL1_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: mCAssTGgtsskyrrcsGTTr
Weblogo:
PSSM: P0 A C G T
01 1760 1703 636 352 m
02 31 4452 32 6 C
03 4452 24 63 11 A
04 57 2080 2372 7 s
05 0 2277 2175 39 s
06 52 21 16 4452 T
07 10 19 4452 29 G
08 246 502 2682 1021 g
09 876 1074 925 1576 t
10 968 1140 1895 449 s
11 876 1235 1254 1087 s
12 884 901 1492 1175 k
13 832 1289 1066 1264 y
14 1369 525 1890 668 r
15 2212 166 1184 891 r
16 899 4452 353 1231 c
17 608 2676 1776 163 s
18 4 14 4452 395 G
19 37 80 220 4452 T
20 242 174 195 4452 T
21 2709 283 1743 698 r
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
MYBL1_TF1 (Myb-like DNA-binding domain, Myb-like DNA-binding domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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