DNA Binding Motif

						

			
Accessions: ETV7_TBX21_2 (HumanTF2 1.0)

			
Names: ETV7_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: mCCGGAAryrmbhTCaCACcy
Weblogo: 
PSSM: P0      A      C      G      T
01    112    142     67     20      m
02     37    270     71      9      C
03     62    341     14      0      C
04      2      0    341      0      G
05      0      0    341      0      G
06    341     38      0      7      A
07    341      7      0      9      A
08    136     28    205      2      r
09     35    142     20    144      y
10    133     76    115     16      r
11    111    139     63     29      m
12     43    110     98     90      b
13    104     89     48    101      h
14      3     20      3    341      T
15     74    341     44     41      C
16    341     44    107     50      a
17      0    341      2      7      C
18    341      2     79      0      A
19     31    341     24      0      C
20     63    210     26     43      c
21     22     94     43    183      y
Type: Heterodimer
Binding TFs: TBX21_TF2 (T-box)
ETV7_TF1 / ETV7_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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