DNA Binding Motif

Accessions: IRF3_methyl_1 (HT-SELEX2 May2017)
Names: IRF3
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Length: 22
Consensus: kCdGTTTCCwGGAAAcyrAaAc
Weblogo:
PSSM: P0 A C G T
01 235 455 8391 3589 k
02 170 12636 13 1888 C
03 3188 62 3997 5423 d
04 1046 3298 11444 564 G
05 455 1 1 12610 T
06 282 3 1 12670 T
07 1 526 0 12670 T
08 2 12670 2 9 C
09 1063 12586 1155 767 C
10 4741 2869 91 4969 w
11 272 2145 12519 661 G
12 238 1 12669 13 G
13 12665 0 22 2 A
14 12670 0 2 84 A
15 12605 34 2 340 A
16 2893 10927 2145 199 c
17 3029 6145 2007 4461 y
18 4673 1 9595 2 r
19 11374 2636 1458 35 A
20 10544 1873 40 3303 a
21 12477 1066 54 1356 A
22 2572 8694 3436 1034 c
Binding TFs: IRF3 (Interferon regulatory factor transcription factor)
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

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