DNA Binding Motif

Accessions: TEAD4_GATA3 (HumanTF2 1.0)
Names: TEAD4_GATA3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: wGATAAsrrwGGAATGy
Weblogo:
PSSM: P0 A C G T
01 156 19 0 96 w
02 5 43 267 9 G
03 267 0 15 0 A
04 0 4 8 267 T
05 267 2 8 45 A
06 267 24 0 59 A
07 20 112 156 0 s
08 97 34 125 11 r
09 96 42 85 44 r
10 107 46 31 83 w
11 45 0 223 17 G
12 55 16 267 23 G
13 220 37 5 48 A
14 267 14 14 7 A
15 2 17 6 267 T
16 0 0 267 41 G
17 43 112 27 155 y
Type: Heterodimer
Binding TFs: GATA3_TF2 (GATA zinc finger)
TEAD4_TF1 (TEA/ATTS domain family)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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