DNA Binding Motif

Accessions: MYBL1_FIGLA_2_3 (HumanTF2 1.0)
Names: MYBL1_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: vCAssTGgyrsrdkrrcsGTyr
Weblogo:
PSSM: P0 A C G T
01 688 1170 675 84 v
02 79 2617 43 77 C
03 2617 47 37 80 A
04 16 839 1778 17 s
05 15 1447 1171 47 s
06 58 0 25 2617 T
07 10 22 2617 44 G
08 284 301 1402 630 g
09 431 898 582 706 y
10 885 611 813 309 r
11 272 919 786 640 s
12 807 620 680 510 r
13 663 450 778 726 d
14 471 619 660 867 k
15 839 181 1025 573 r
16 1331 120 704 463 r
17 725 2617 275 384 c
18 413 1728 889 160 s
19 133 33 2617 423 G
20 141 215 126 2617 T
21 329 1194 335 2617 y
22 1641 185 976 412 r
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
MYBL1_TF1 (Myb-like DNA-binding domain, Myb-like DNA-binding domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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