DNA Binding Motif

						

			
Accessions: PITX1_HOXA3 (HumanTF2 1.0)

			
Names: PITX1_HOXA3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: taATkrgkgkgGATTA
Weblogo: 
PSSM: P0      A      C      G      T
01     33     16     19    138      t
02    138     19     38     19      a
03    138      8      7     16      A
04     17     18     28    138      T
05     16     32     63     75      k
06     66     36     72     18      r
07     20     31     55     32      g
08     29     26     40     43      k
09     25     34     51     28      g
10     34     26     40     38      k
11     37     13    138     16      g
12     33      9    138      9      G
13    138     22      4      9      A
14      1      1      1    138      T
15      4     11      4    138      T
16    138      4      4     22      A
Type: Heterodimer
Binding TFs: PITX1_TF1 / PITX1_TF2 (Homeobox domain)
HOXA3_TF1 / HOXA3_TF2 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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