DNA Binding Motif

Accessions: 1bc8_C (3D-footprint 20231221)
Names: PROTEIN (SAP-1 ETS DOMAIN)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: STRUCTURES OF SAP-1 BOUND TO DNA SEQUENCES FROM THE E74 AND C-FOS PROMOTERS PROVIDE INSIGHTS INTO HOW ETS PROTEINS DISCRIMINATE BETWEEN RELATED DNA TARGETS
Length: 5
Consensus: CGGAa
Weblogo:
PSSM: P0 A C G T
01 0 80 0 16 C
02 0 0 96 0 G
03 0 0 96 0 G
04 80 0 16 0 A
05 48 16 16 16 a
Binding TFs: 1bc8_C (Ets-domain)
Binding Sites: 1bc8_A
1bc8_B
Publications: Mo Y., Vaessen B., Johnston K., Marmorstein R. Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins.. Mol. Cell 2:201-212 (1998). [Pubmed]

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