DNA Binding Motif

						

			
Accessions: MA0620.3 (JASPAR 2024)

			
Names: MITF
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 18
Consensus: wwwrrTCACGTGAyywww
Weblogo: 
PSSM: P0      A      C      G      T
01  16903  14427  14387  17810      w
02  17916  14092  15140  16379      w
03  20979  11587  14438  16523      w
04  23673   7202  18498  14154      r
05  19441   5205  36761   2120      r
06   2416   4997   2991  53123      T
07    237  62666    416    208      C
08  61547    751    469    760      A
09    313  47772   1140  14302      C
10  14306   1140  47768    313      G
11    759    469    751  61548      T
12    208    416  62666    237      G
13  53124   2990   4999   2414      A
14   2119  36765   5204  19439      y
15  14149  18498   7207  23673      y
16  16527  14437  11586  20977      w
17  16378  15135  14097  17917      w
18  17807  14383  14433  16904      w
Type: Heterodimer
Binding TFs: O75030 (Helix-loop-helix DNA-binding domain, Domain of unknown function (DUF3371))
O75030
Binding Sites: MA0620.3.19
MA0620.3.20
MA0620.3.1
MA0620.3.10
MA0620.3.11
MA0620.3.12
MA0620.3.13
MA0620.3.14
MA0620.3.13 / MA0620.3.15
MA0620.3.14 / MA0620.3.16
MA0620.3.15 / MA0620.3.17
MA0620.3.16 / MA0620.3.18
MA0620.3.17 / MA0620.3.19
MA0620.3.2
MA0620.3.18 / MA0620.3.20
MA0620.3.3
MA0620.3.4
MA0620.3.5
MA0620.3.6
MA0620.3.7
MA0620.3.8
MA0620.3.9
MA0620.3.1
MA0620.3.2
MA0620.3.3
MA0620.3.4
			
Publications: McGill G. G., Horstmann M., Widlund H. R., Du J., Motyckova G., Nishimura E. K., Lin Y. L., Ramaswamy S., Avery W., Ding H. F., Jordan S. A., Jackson I. J., Korsmeyer S. J., Golub T. R., Fisher D. E. Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability.. Cell 109:707-718 (2002). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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