DNA Binding Motif

						

			
Accessions: GCM2_SOX15_2_3_4 (HumanTF2 1.0)

			
Names: GCM2_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: aTRcGGGygaaaACAATr
Weblogo: 
PSSM: P0      A      C      G      T
01    288     58     79      9      a
02     30     14      0    367      T
03    108     10    260      0      R
04     68    367    102     38      c
05      0      1    367     14      G
06      0      1    367     23      G
07      0      3    367      4      G
08     69    145     23    130      y
09     72     82    168     46      g
10    178     82     56     50      a
11    259     70    109    100      a
12    186     30     75     76      a
13    367     15     35     49      A
14      0    367     13     94      C
15    367     24      0     22      A
16    367     14      0     47      A
17     90     15     12    278      T
18    138      9    174     46      r
Type: Heterodimer
Binding TFs: GCM2_TF1 (GCM motif protein)
SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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