DNA Binding Motif

						

			
Accessions: 2as5_N (3D-footprint 20231221)

			
Names: Nuclear factor of activated T-cells, cytoplasmic 2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of the DNA binding domains of NFAT and FOXP2 bound specifically to DNA.
Length: 7
Consensus: TTtTCCT
Weblogo: 
PSSM: P0      A      C      G      T
01      0      7      7     82      T
02     14     14      0     68      T
03     14      7     16     59      t
04      0      0      0     96      T
05      0     96      0      0      C
06      0     96      0      0      C
07      9      7      7     73      T
Binding TFs: 2as5_N (Rel homology domain (RHD), IPT/TIG domain)
Binding Sites: 2as5_B
2as5_A
			
Publications: Wu Y, Borde M, Heissmeyer V, Feuerer M, Lapan A.D, Stroud J.C, Bates D.L, Guo L, Han A, Ziegler S.F, Mathis D, Benoist C, Chen L, Rao A. FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell 126:375-87 (2006). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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