DNA Binding Motif

Accessions: 2as5_N (3D-footprint 20231221)
Names: Nuclear factor of activated T-cells, cytoplasmic 2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of the DNA binding domains of NFAT and FOXP2 bound specifically to DNA.
Length: 7
Consensus: TTtTCCT
01 0 7 7 82 T
02 14 14 0 68 T
03 14 7 16 59 t
04 0 0 0 96 T
05 0 96 0 0 C
06 0 96 0 0 C
07 9 7 7 73 T
Binding TFs: 2as5_N (Rel homology domain (RHD), IPT/TIG domain)
Binding Sites: 2as5_B
Publications: Wu Y, Borde M, Heissmeyer V, Feuerer M, Lapan A.D, Stroud J.C, Bates D.L, Guo L, Han A, Ziegler S.F, Mathis D, Benoist C, Chen L, Rao A. FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell 126:375-87 (2006). [Pubmed]

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