DNA Binding Motif

						

			
Accessions: FOXO1_ELK3_1 (HumanTF2 1.0)

			
Names: FOXO1_ELK3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 12
Consensus: rcCGGAwGTkkw
Weblogo: 
PSSM: P0      A      C      G      T
01    624    125    425    152      r
02    204   1048    367    131      c
03    135   1048     79      0      C
04      0      1   1048      0      G
05      3      0   1048     30      G
06   1048     31     27     22      A
07    624     13     29    424      w
08    136     39   1048      6      G
09     76    175     84   1048      T
10    209     95    387    661      k
11    314    186    470    578      k
12    473    229    335    576      w
Type: Heterodimer
Binding TFs: ELK3_TF2 (Ets-domain)
FOXO1_TF1 / FOXO1_TF2 (Fork head domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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