DNA Binding Motif

						

			
Accessions: TEAD4_ELF1_1 (HumanTF2 1.0), UN0582.1 (JASPAR 2024)

			
Names: TEAD4_ELF1, TEAD4::ELF1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 14
Consensus: rgAATGCGGAAGtr
Weblogo: 
PSSM: P0      A      C      G      T
01   1891    448   3241    795      r
02    507   1057   3688    565      g
03   3829    408     95    909      A
04   4093     36     36    170      A
05     47    553     75   3980      T
06     63    238   4082     45      G
07    247   4060     56     36      C
08     24     51   4148     36      G
09     63     33   4136     41      G
10   4122     66     38    163      A
11   4014    149     52    458      A
12    935    426   3793    126      G
13    664    947    483   3599      t
14   1592    568   1378    610      r
Type: Heterodimer
Binding TFs: ELF1_TF2 (Ets-domain, Transcription factor protein N terminal)
TEAD4_TF1 (TEA/ATTS domain family)
Q15561 (TEA/ATTS domain family)
Q15561
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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