DNA Binding Motif

						

			
Accessions: FLI1_CEBPD (HumanTF2 1.0), UN0527.1 (JASPAR 2024)

			
Names: FLI1_CEBPD, FLI1::CEBPD
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 17
Consensus: rmmGGAwATTGCGcAAy
Weblogo: 
PSSM: P0      A      C      G      T
01    301     53    176    111      r
02    137    195    105     41      m
03    218    477     32     12      m
04      7      7    477      4      G
05      0      9    477      2      G
06    477      0      4      0      A
07    231     21     25    200      w
08    355      5    116      0      A
09      0      2      2    477      T
10      0      2     37    477      T
11    145      0    477     42      G
12     13    477      0     45      C
13     51      0    477      4      G
14    164    477      6    189      c
15    477     28     12      0      A
16    477      0      0      2      A
17      0    128     57    293      y
Type: Heterodimer
Binding TFs: Q01543 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
CEBPD_TF2 (bZIP transcription factor, Basic region leucine zipper)
FLI1_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FLI1_Full (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
Q01543
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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