DNA Binding Motif

Accessions: GCM2_TBX21_2 (HumanTF2 1.0)
Names: GCM2_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: ATGmGGGCTAGGTGtGA
Weblogo:
PSSM: P0 A C G T
01 3703 87 5 113 A
02 0 59 107 3754 T
03 104 0 3195 611 G
04 1748 3908 572 446 m
05 120 398 3908 93 G
06 0 90 3908 274 G
07 40 0 3908 220 G
08 158 2794 132 825 C
09 105 837 148 2818 T
10 3536 0 224 151 A
11 642 273 3908 485 G
12 447 232 3908 180 G
13 424 252 800 3908 T
14 487 153 3908 65 G
15 721 1147 243 3908 t
16 754 157 2856 141 G
17 3537 100 154 116 A
Type: Heterodimer
Binding TFs: GCM2_TF1 (GCM motif protein)
TBX21_TF2 (T-box)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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