DNA Binding Motif

						

			
Accessions: UP00236A_1 (UniPROBE 20160601)

			
Names: Homeodomain protein IRXA2, Iroquois homeobox protein 2, Iroquois related homeobox 2 (Drosophila), Iroquois-class homeodomain protein IRX-2, Irx2, IRX6, MGC103290
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 17
Consensus: wwdrTACATGTAarwkw
Weblogo: 
PSSM: P0      A      C      G      T
01   0.39   0.08   0.10   0.42      w
02   0.47   0.13   0.13   0.28      w
03   0.32   0.13   0.26   0.30      d
04   0.41   0.14   0.25   0.20      r
05   0.22   0.01   0.03   0.74      T
06   0.95   0.01   0.01   0.03      A
07      0   0.97   0.01   0.01      C
08   0.96      0   0.01   0.03      A
09   0.03   0.01      0   0.96      T
10   0.01   0.01   0.97      0      G
11   0.03   0.01   0.01   0.95      T
12   0.74   0.03   0.01   0.22      A
13   0.40   0.17   0.21   0.21      a
14   0.30   0.19   0.29   0.22      r
15   0.40   0.11   0.12   0.37      w
16   0.18   0.20   0.27   0.36      k
17   0.34   0.11   0.08   0.47      w
Binding TFs: UP00236A (Homeobox domain, Homeobox KN domain)
Binding Sites: AAACATGT
AACATGTA
AACATGTT
ACACGTGT
ACATGTAA
ACATGTAC
ACATGTAG
ACATGTAT
ACATGTTA
ACATGTTC
AGTACAAG
ATGTACAA
ATGTACAT
CATACATG
CATGTAAC
CATGTACA
CTTGTACA
GCTTGTAC
GTACAACA
GTACAAGA
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.