DNA Binding Motif

						

			
Accessions: ELF1_DBD (HumanTF 1.0), MA0473.2 (JASPAR 2024)

			
Names: ELF1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 7, HT-SELEX
Length: 12
Consensus: aACCCGGAAGTr
Weblogo: 
PSSM: P0      A      C      G      T
01   3447    515    880   1042      a
02   3447    342    160    566      A
03    625   3447    301    314      C
04     98   3447    257      0      C
05    116   3447      0      0      C
06      0      0   3447      0      G
07      0      0   3447      0      G
08   3447      0      6      0      A
09   3447      1      0     59      A
10    539      0   3447      1      G
11     34    299      0   3447      T
12   1042    656   1354    394      r
Type: Heterodimer
Binding TFs: ELF1_DBD (Ets-domain)
P32519 (Ets-domain, Transcription factor protein N terminal)
P32519
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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