DNA Binding Motif

						

			
Accessions: TEAD4_EOMES_2_3_4_5_6 (HumanTF2 1.0)

			
Names: TEAD4_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: rgGTGtkrssrkwGGwATGyg
Weblogo: 
PSSM: P0      A      C      G      T
01     96     10     46     23      r
02     26     37    143     31      g
03      3      1    143     17      G
04      1     24      3    143      T
05     11      0    143      0      G
06     28     42     16    143      t
07     23     30     47     44      k
08     72      3     54     14      r
09     16     46     46     35      s
10     17     49     42     35      s
11     38     28     47     29      r
12     31     20     49     43      k
13     44     32     22     44      w
14     18      0    118      8      G
15     14     14    143     14      G
16    143     15      0     80      w
17    143      7      9      0      A
18      7      2     13    143      T
19      4      9    143     15      G
20     10     89      5     54      y
21     32     29     59     23      g
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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