DNA Binding Motif

						

			
Accessions: TEAD4_TCF3 (HumanTF2 1.0)

			
Names: TEAD4_TCF3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: rCAGsTGmGwATkyr
Weblogo: 
PSSM: P0      A      C      G      T
01    355    213    605    172      r
02    101   1344      0     49      C
03   1344      0      0      7      A
04      0    187   1344     70      G
05     75    724   1344     31      s
06      0     13     11   1344      T
07     18      9   1344     27      G
08    532    429    238    144      m
09    109    159   1344    100      G
10    697    183     60    646      w
11   1344     41     79     30      A
12      1    202     46   1344      T
13     45    163   1344    651      k
14    129    624    171    720      y
15    405    265    477    196      r
Type: Heterodimer
Binding TFs: TCF3_TF2 (Helix-loop-helix DNA-binding domain)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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