DNA Binding Motif

						

			
Accessions: HOXD12_ETV4_1 (HumanTF2 1.0)

			
Names: HOXD12_ETV4
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: rCCGGAAGTaATAAAm
Weblogo: 
PSSM: P0      A      C      G      T
01   4192   1481   3189    290      r
02    641   6789    591    103      C
03    531   7381      0     19      C
04     29      0   7381      0      G
05      2      0   7381      8      G
06   7381      8      0      5      A
07   7381      0     24    295      A
08     74     59   7381     29      G
09     22   1244     13   7381      T
10   7381   2494    869    171      a
11   7381     50    737     18      A
12      0     23      0   7381      T
13   7381    148     70   1550      A
14   7381      0      0      0      A
15   7381    131      0    101      A
16   3385   2576    721    699      m
Type: Heterodimer
Binding TFs: ETV4_TF2 (Ets-domain)
HOXD12_TF1 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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