DNA Binding Motif

						

			
Accessions: GCM1_ERG (HumanTF2 1.0)

			
Names: GCM1_ERG
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: rTGCGGGCGGaarkg
Weblogo: 
PSSM: P0      A      C      G      T
01    115     27     52     10      r
02      0      8     20    167      T
03     38      0    128      2      G
04      0    133     14     34      C
05      1      0    167      0      G
06      0      7    167      0      G
07      4      0    167      0      G
08     17    167     34      9      C
09      1      0    167     23      G
10     14     14    167      8      G
11    167     12     43     53      a
12    167      7     52     54      a
13     60      3    107     14      r
14      8     25     80     87      k
15     28     18    103     17      g
Type: Heterodimer
Binding TFs: ERG_TF1 / ERG_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
GCM1_TF1 (GCM motif protein)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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