DNA Binding Motif

Accessions: UP00086A_2 (UniPROBE 20160601)
Names: C920001K05Rik, interferon regulatory factor 3, IRF-3, Irf3, MGC91046
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 14
Consensus: ggagAAwGGwscra
Weblogo:
PSSM: P0 A C G T
01 0.24 0.15 0.41 0.20 g
02 0.20 0.14 0.44 0.23 g
03 0.60 0.09 0.12 0.19 a
04 0.21 0.06 0.65 0.08 g
05 0.75 0.03 0.05 0.18 A
06 0.77 0.05 0.04 0.14 A
07 0.48 0.09 0.18 0.26 w
08 0.06 0.11 0.75 0.07 G
09 0.06 0.07 0.82 0.05 G
10 0.27 0.09 0.22 0.42 w
11 0.06 0.38 0.42 0.13 s
12 0.05 0.60 0.17 0.19 c
13 0.27 0.15 0.38 0.20 r
14 0.38 0.20 0.22 0.20 a
Binding TFs: UP00086A (Interferon regulatory factor transcription factor)
Binding Sites: AAAGGAAA
AAGGAAAC
ACCGAAAC
AGAAAGGA
AGGAAACT
AGTTTCCA
AGTTTCGA
ATCGAAAC
ATGGAAAC
CAGTTTCC
CGAAACCG
CGGTTTCC
GAAACCAA
GGAAACTA
GGTTTCCA
GTTTCCAA
GTTTCGAA
GTTTCGGA
TTTCCAAA
TTTCGAAA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

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